Answer Posted / nidhi srivastava

In the majority of the cases the analytical method of
choices is either GC or HPLC. GC generally selected where
the compounds to be analysed are volatile, of low molecular
weight, thermally stable and non polar.In HPLC methods
developed for analytical work with picograms, nanograms of
compounds are simply transferred to larger columns to higher
flow rates for preparative chromatography for the isolation
of milligrams or grams of compounds. Similar scale
preparative GC would be impractical, if not impossible, in
the laboratory.

if instrument calibration fails then what require to do?

1017

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Is it nessesary all multimedia dissolution require descriminatory?

859

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how can give the expiry period and restadardisation of volumetric solution

2642

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in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?

886

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While performing TOC sst analysis Zero shift disabled & sample analysis zero shift enabled why?

2900

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In which situation we require to prepare the standard solution from sample in Related substance method?

824

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what is definition of validation? which components are followed give detail?

2446

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UV and PDA detector, which have less signal to noise ratio?

1177

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what is the extinction coefficient for Indomethacin or at 319nm wave length.

4125

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why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?

1752

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WHY pKa value is more important than pH value of the mobile phase in HPLC?

1810

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[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?

849

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In Assy by potentio metry titration method how select MET U ,DET U, SET U,

2241

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what is turbidimetric titration?Give 2 examples.

2732

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if you have given a blank water how you analyse by general analytical techniques?

2083

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