what is LC - MS ? What its wide use in cro/pharmaceutical
Industry
Answer Posted / mithu
lc-ms is nothing but hplc/uplc attached to a mass spectrometer by which the seperation as well as identification on the basis of m/z is possible.Its use in cro and pharmaceuticals is much in new molecule development.
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please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development
My question about gas chromatography sulfur chemiluminsecence detector. I test unknown sample gas by GC-SCD (calibrated ) and the result of *H2S is 279 PPM , *but when I test the same sample with the GC-TCD (calibrated ) the value of *H2S is 2500 PPM . I'd like to inform you that both GCs are calibrated and have very good operation conditions with stable parameters . the question is if the sample gas with higher H2S over detection limits of SCD detector (1000 ppm). why the result it 279 ppm Best regards
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