What is the difference between Optical rotation and Spcefic
optical rotation
Answer Posted / sanjay bute
Optical rotation is the turning of the plane of linearly
polarized light about the direction of motion as the light
travels through certain materials. It means it is only a
measure of degree of polarised light.
But Specific optical rptation is the observed angle of
optical rotation (α) when plane-polarized light is passed
through a sample with a path length of 1 decimeter and a
sample concentration of 1 gram per 1 millilitre
optical rotaion(α)
Specific optical rotation = -------------------
path length in decimeters x C
C = concentration in g/ml
The specific optical rotation is Temperature dependent and
also it depends on wavelength of light used for measurement
Generally the sodium D line is used at 589 nm for
measurement.
| Is This Answer Correct ? | 12 Yes | 0 No |
Post New Answer View All Answers
1)What's the meaning of Absorption,give a example. 2)What's the meaning of Adsorption,give a example. 2)what is the difference between Absorption and Adsorption.
how you fix the limits of impurities?
If we have 5 strength which is not dose proportinate and excipients also diffrent in each strength then how we can proceed for Force degradation? and excipient are same but not dose propotinate the how FD?
if you have given a blank water how you analyse by general analytical techniques?
how we can identify the impurity is coming below loq at transfering site?
What is gelatinization?
if identification threshold crosses the limits then what next step?
why we use a particular hplc column for a particular compound give reasons?please
If vendor having more imp than monograph then how to proceed? and how to set spec?
How to set specification of assay, fisdolution and related substances?
As per ICH related substances stability trend limit from initial to shelf life
Why six unit used for precision?
What is intact assay method development.....?
In which situation we require to analytical method validation of excipient?
what is mean by peak intigrity?