Interested to Buy Any Domain ? << Click Here >> for more details...
What is the difference b/w OVI Solvents and Residual
Solvents in case of Gas Chromatogaphy and What is its
Detection Limit?
- 8 Answers
- 39346 Views
- Jubilant Organosys, Suven Life Sciences, I also Faced
- E-Mail Answers
Answer Posted / venkatesh
For pharmacopeial purposes, residual solvents in
pharmaceuticals are defined as organic volatile chemicals
that are used or produced in the manufacture of drug
substances or excipients, or in the preparation of drug
products. The residual solvents are not completely removed
by practical manufacturing techniques. Appropriate
selection of the solvent for the synthesis of a drug
substance or an excipient may enhance the yield, or
determine characteristics such as crystal form, purity, and
solubility. Therefore, the solvent may sometimes be a
critical element in the synthetic process. This General
Chapter does not address solvents deliberately used as
excipients nor does it address solvates. However, the
content of solvents in such products should be evaluated
and justified.
| Is This Answer Correct ? | 4 Yes | 2 No |
Post New Answer View All Answers
why require the ph, buffer during hplc mobile phase?
how you start RS method development when for new product?
function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?
how much mass should be there in volumetric flask while in preparation of sample for assay?
In the isomers,enantiomers give the only physical properties present such that no chemical properties present.
Please tell me about the pH of Polycaboxylic ether is it in the 5-6 range ever or more than 6
How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?
For limit test of heavy metals in BP, Method C require that the substance is ignited at a temperature not exceeding 800 °C. Why confines such the temperature?
what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me
Please give idea about method development for cleaning method and how maco level establish
what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.
4. Describe the operation of the Craig apparatus. Chapter.3 Equilibrium Processes in Separations
While performing TOC sst analysis Zero shift disabled & sample analysis zero shift enabled why?
from where i get mortar pastle for glass bottle crush? it's required for testing of it?
what is the extinction coefficient for Indomethacin or at 319nm wave length.
