Answer Posted / venkatesh

For pharmacopeial purposes, residual solvents in
pharmaceuticals are defined as organic volatile chemicals
that are used or produced in the manufacture of drug
substances or excipients, or in the preparation of drug
products. The residual solvents are not completely removed
by practical manufacturing techniques. Appropriate
selection of the solvent for the synthesis of a drug
substance or an excipient may enhance the yield, or
determine characteristics such as crystal form, purity, and
solubility. Therefore, the solvent may sometimes be a
critical element in the synthetic process. This General
Chapter does not address solvents deliberately used as
excipients nor does it address solvates. However, the
content of solvents in such products should be evaluated
and justified.

how to develop the icp ms method? Application of icp ms?

850

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How to set analyticl specification for combination products?

799

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if content uniformity passing but dissolution varrying then what is next step?

937

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what type of question will ask in the interview of lab chemist.

3365

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if rsd failed then what require to do?

886

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Which parameters require to do in tech transfer?

819

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in sampling of raw material which side is pasted sampled labels

1888

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why does used dry caffien in HPLC calibration?

2082

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WHAT IS THE CRITERIA FOR SELECTION OF TIME OF DISSOLUTION AND THE MEDIUM OF DISSOLUTION?

2626

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UV and PDA detector, which have less signal to noise ratio?

1178

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What if impurity area in control sample coming more as compared to LOQ level of impurity ?

1652

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WHAT IS THE PARAMETER FOR THE SELECTION OF MOBILE PHASE IN HPLC?

1251

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calibrtion procedue of LC-MS

2761

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4. Describe the operation of the Craig apparatus. Chapter.3 Equilibrium Processes in Separations

2771

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In the HPLC Calibration done wavelength accuracy done between 200nm-280nm .but not done remaining 300-400nm not done ?

976

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