Answer Posted / jagadeeshchandra
#Base line is nothing but the detectors response to the
mobile phase.(gc,hplc)
#Base line should be stable to start a run.
#Un stabilized base line is called as base line noise.
#Base line noise is of many types..
1)Cyclic base line
2)Synchorinise noise
3)Asynchorinise noise
4)Base line drift
5)Spikes
6)Negative peaks
7)No peaks
#Base line noise is attributed due to mobile phase,sample,
system problems.leaks in the system,temperature variations
in lab etc..
| Is This Answer Correct ? | 14 Yes | 1 No |
Post New Answer View All Answers
please explain about aluminium hydroxide assay
What is mean by PDR?
How do we fix the sample concentaryion in hplc method development. What is the basis?
what are the standard methods for HPLC?
how require to select dissolution media? what is discrimination?
In which situation we require to prepare the standard solution from sample in Related substance method?
How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain
What is importance of pH in the Heavy metal test and How it effect on the test results?
Why six unit used for precision?
Please give idea about method development for cleaning method and how maco level establish
What is the purpose of octyl silane columns?
how many types of balance calibration test?
identification is for unknown? qualification for known? reporting for LOQ?
in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?
