Answer Posted / subash

In KF titration the reaction takes place between I2, SO2,
Methnol and H2O and base acts as a buffer inorder to keep
the pH of the solution between 5.5 and 8.0.

methnol+ SO2+base gives intermediate alkyl sulphite salt
which is then oxidized by I2to an alkyl sulphate salt. This
oxidation reaction consumes water.

from where i get mortar pastle for glass bottle crush? it's required for testing of it?

2252

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before starting analytical method valodation what you checking? and how giving preference to start validation?

779

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What is Band broading effect explain

1861

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how you fix the limits of impurities?

822

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what is turbidimetric titration?Give 2 examples.

2638

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In Dissolution Test why limit is define Q+5% what is the role of +5%.

3081

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Which is the highly polar and highly non polar column in HPLC?

2283

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How to calibration of the uv spectroscopy and its test?

1178

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If we have 5 strength which is not dose proportinate and excipients also diffrent in each strength then how we can proceed for Force degradation? and excipient are same but not dose propotinate the how FD?

787

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What is the diference between residual solvents and organic volatile matter

2010

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Which parameters require to do in tech transfer?

735

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Ratio of Water and Acetonitrile(diluent) is not recommended to use in cleaning method validation,why?

2941

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How to establish relative response factor for hplc. Why it is required?

1198

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If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

837

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please explain about aluminium hydroxide assay

1116

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