what is the difference between M.C and LOD
- 21 Answers
- 65882 Views
- Aurobindo, Cipla, Laurus, Matrix, Synthokem Labs, I also Faced
- E-Mail Answers
Answer Posted / swarupa kumar behera
M/c (moisture content) - It determine that how many quantity of water present in supplied sample. It generally check by Karlfisher.
LOD ( lose on Drying)- determine both water and non-volatile substance in supplied sample. It done in oven at 110'C for 1hr.
| Is This Answer Correct ? | 9 Yes | 2 No |
Post New Answer View All Answers
in sampling of raw material which side is pasted sampled labels
Please give idea about method development for cleaning method and how maco level establish
In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.
Why sodium hydroxide used for maintain pH of phosphate buffer
Why to use propyl paraben in HPLC gradient calibration
Loss of linearity in tkn analysis, possible reasons?
USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...
How to calculate coreletion coefficient
please explain about aluminium hydroxide assay
what is %labelled amount in content uniformity of dosage unit and its calculation?
In the HPLC Calibration done wavelength accuracy done between 200nm-280nm .but not done remaining 300-400nm not done ?
How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.
we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion
How to determine water content of bis tetrazole amine mono ammonium salt
Related substance method equivalency on control sample or spiked sample?
