Interested to Buy Any Domain ? << Click Here >> for more details...
what is the difference between gc& hplc. why we r not
calculating purity by gc for final products
- 5 Answers
- 17253 Views
- Biocon, Cipla, I also Faced
- E-Mail Answers
Answer Posted / dhanalakshmi
Gas chromatography (GC) is based on a partition equilibrium
of analyte between a solid stationary phase (often a liquid
silicone-based material) and a mobile gas (most often Helium).
In the HPLC technique, the sample is forced through a column
that is packed with a stationary phase composed of
irregularly or spherically shaped particles, a porous
monolithic layer, or a porous membrane by a liquid (mobile
phase) at high pressure
GC is used for volatile compounds (those that break down
rapidly) while HPLC is better for less volatile samples. If
a sample contains salts or carries a charge, it must be
analyzed using HPLC, not GC
GC is used for volatile compounds (those that break down
rapidly) while HPLC is better for less volatile samples. If
a sample contains salts or carries a charge, it must be
analyzed using HPLC, not GC
| Is This Answer Correct ? | 25 Yes | 3 No |
Post New Answer View All Answers
Did anybody have method for acetyl cysteine effervescnce tablet
how we can identify the impurity is coming below loq at transfering site?
What is similarity factor and its use in api strength?
Why we select scan range from higer wavelength to lower wavelength in uv visible spectroscopy and ftir spectroscopy ? .
If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately
If we have 5 strength which is not dose proportinate and excipients also diffrent in each strength then how we can proceed for Force degradation? and excipient are same but not dose propotinate the how FD?
Principle of single pan analytical balance
Qc interview questions
Which are the diffrent grades of api in pharma?
what is definition of validation? which components are followed give detail?
What is importance of pH in the Heavy metal test and How it effect on the test results?
process of Diclofenac sodium,IP.
how to develop the icp ms method? Application of icp ms?
please explian me about area normalisation method,diluted standard method,impurity vs impurity and which one has to be selected in method development
Describe your field experience sample type collected,sample techniques,field measurements taken and equipment used?
