How you can calculate pKa ?

Answer Posted / pratap rasam

Carry out acid-base titration and note down the
readings.Plot a graph of pH nersus volume of titrant added.
Locate the equivalence point. Compute the volume exactly
half the equivalent point and from this volume
corresponding pH is nothing but pKa.

Is This Answer Correct ?    12 Yes 1 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

USP methodology, EP methodology, IP methodology, among three if possible to use one methodology for qualify working standard to use USP, EP, IP ? Please explain...

1548


If inhouse hplc related substance method is completly diffrent from Usp for finished proďuct with diffrent impurities then how require to prove method equivalecy?

304


identification is for unknown? qualification for known? reporting for LOQ?

272


why digestion require in icpms?

297


How to fix the sample conc. in Related substances test by HPLC?

605






What is the accrptance criteria in RSD for RS method precision on basis of impurity percentages?

300


Explain the relations between number of carbon atoms in alkanes and retention time ?

1620


if your product is soluble in 0.1n hcl and water then which you choose as media from these 2 media?

269


how can I make the copper get white bye any salt or acit?

1660


what is mean by extactable and leachable study?

557


if you get peak in blank then what require to do?

474


what is the importance of peak purity in HPLC and how we can calculate through manul(not software)?

3982


In Dissolution Test why limit is define Q+5% what is the role of +5%.

2565


in dissolution why pool sample needed? in which type of drug pool sample need?

2586


Why dissolution test is not performed in all of the products

2021