Answer Posted / ramesh babu

First reject the product and raise the OOS.

what are the standard methods for HPLC?

2830

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what is lod and loq ?,why use k2cr2o7 , kcl h2so4 in uv calibration ?,why use benzophenone & caffene acetone in hplc calibration ?,what is leading peak in hplc ?why we do the calibration of limit of stry light in hplc & uv ?

3723

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Why potassium dichromate is used in calibration of uv?

2038

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In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.

3188

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How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?

3397

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Loss of linearity in tkn analysis, possible reasons?

1363

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how we can identify the impurity is coming below loq at transfering site?

930

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what is the disso medium for tropsiun chloride

2309

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If vendor having more imp than monograph then how to proceed? and how to set spec?

1001

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IS THERE ANY EQUIPMENT TO CHECK AND CALCULATE THE POLARITY OF A LIQUID?

2506

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Which products will produce when acetic anhydride reacts with Ter-butanol, Sec-butanol, Iso butanol, Dimethylamine etc.

2911

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How to set analytical specification for combination products?

870

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How to know the estimated LOQ concentration in ppm

1275

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is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth

2216

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Why acetonitrile and water are used as extraction solvent when analysis melamine? I thought they are miscible and won't be able to separate...

1750

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