what is the need of calulation of RRF of impurity in HPLC
analysis?

Answer Posted / ramesh babu

Generally RRF will calculate in impurity analysis. The
impurity standards are very cost effectives and some times
not avalible. It is not possible to use the impurity
standard at each time of the impurity analysis.During the
method development time we need to calculate RRF against
with standard.

Is This Answer Correct ?    44 Yes 9 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

which are the sizes of capsules?

393


what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means

1480


how the compound separate in coulunm,explain

1932


How to know the estimated LOQ concentration in ppm

721


how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.

1822






EXPLAIN THE CALCULATION PART OF AN KF TITRATOR CALIBRATION WITH SUITABLE EXAMPLE

2117


what is classification of elemental impurities? what is risk assement in elemental impurities?

328


acceptance criteria for lod & loq by standard deviation of response and slope??

2076


what is mean by dissolution biowaiver study?

312


1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer

1293


What is column in chromatography?

1750


how to calculate elemental impurities?

529


which one is better separation in high pressure liquide chromatogram orlowpressure chromato gram in hplc

1714


What is diffrence between extractable volume and deliverable volume? Answer pls

3905


What is Band broading effect explain

1386