Answer Posted / kishore

Bracketing is doing standard injection after every 3
batches to know the performance of the system middle of the
analysis.

in dissolution why pool sample needed? in which type of drug pool sample need?

3180

---

How to establish relative response factor for hplc. Why it is required?

1229

---

What are the primary considerations in extractables and Leachables ?

2277

---

How we choose the mobile phase for method development.?

1213

---

in api coa contains only process impurities and in product coa contains degradation impurities?

701

---

is it nessesary to do solution stability for 7 days?

776

---

Why we select scan range from higer wavelength to lower wavelength in uv visible spectroscopy and ftir spectroscopy ? .

912

---

How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain

2389

---

How to calculation of residual solvent methanol (3000 ppm) standard solution, and how many quantity used of test sample

3244

---

some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

2655

---

what are the guidelines for analytical method validations?

1103

---

what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?

890

---

all types of questions asked at the cipla interview

4685

---

2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.

2224

---

if you have given one product then how you determine the impurity in that?

744

---