Wt s the use of linearity in HPLC method validation

Answer Posted / parag parekh

TO CONFIRM THE RESPONCE of detector & instrument with the
concentration wheter the system is responding properly for
the change in concentration.

Is This Answer Correct ?    2 Yes 2 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

If we have 5 strength which is not dose proportinate and excipients also diffrent in each strength then how we can proceed for Force degradation? and excipient are same but not dose propotinate the how FD?

339


If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

366


What if impurity area in control sample coming more as compared to LOQ level of impurity ?

1160


in which situation ion pair agent require to use?

277


Why are use silicon oil mr?

754






How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?

1315


Why use only methanol,used determinationof moisture content not use other solvents

890


Is it nessesary all multimedia dissolution require descriminatory?

350


what is mean by nitrosamine impurities?

550


How can the GC or HPLC method is selected to determine the impurity profile in drug product?

6877


in dissolution why pool sample needed? in which type of drug pool sample need?

2602


what is procedure of actual procedure for registration of drug?

1464


is it necessary to do HPLC calibration at wavelength 315nm if we are doing analysis at this wavelangth

1671


What is the requirement for brazil in the analytical method vslidation comparr to ich?

278


from where i get mortar pastle for glass bottle crush? it's required for testing of it?

1743