Answer Posted / singi.venkateswararao

i have been working as an analytical chemist in CHEMLOIDS
R&D centre in VIJAYAWADA for 4 1/2 years.I HVE AN EXP TO
HANDLING INSTRUMENTS LIKE HPLC ,UV, IR,ETC.THE PHENOMENON
OF ANALYSE SAMPLES PURITY & WHAT ARE THE OTHER IMPURITIES
IN THEIR USING SPECTROSCOPICAL INSTRUMENTS MAY CALLED
ANALYTICAL INSTRUMENTATION.TO MAINTAIN AN ANALYTICAL
INSTRUMENTS IS NOT EASY LIKE OTHER TECQNICS
TITRIMETRIC,GRAVIMETRIC .HERE MOST OF THE WORK RUNNIG BY
MANUAL.BUT WHERE AS IN INSTUMENTATION DEVISION WE CAN
CONTROL SYSTEMS BY GIVING SHEDULES TO SOME TIME EXTENT.HERE
WE HAVE TO USE ONLY HPLC GRADE SOLVENTS.OTHER WISE OUR
MIGHT DAMAGE.

why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?

1708

---

which batch require to use for analytical method validation?

808

---

what is procedure of actual procedure for registration of drug?

2012

---

What is the difference between chromatographic purity and related substances?

1376

---

Please tell me about the pH of Polycaboxylic ether is it in the 5-6 range ever or more than 6

2609

---

how decide the clining method and cleaning method validation require for this perticular products?

755

---

in each media we require to use SLS? how to proceed?

787

---

if you given one product then which tests you will perform?

709

---

What is stray light in uv what are units for stray light

1652

---

give clarity of linearity and range in method validation

2420

---

how you confirm the assay method?

772

---

IS THERE ANY EQUIPMENT TO CHECK AND CALCULATE THE POLARITY OF A LIQUID?

2457

---

In Dissolution Test why limit is define Q+5% what is the role of +5%.

3105

---

how to qualify the impurity?

874

---

WHICH STANDARD WE USE IN SILICA ANALYSIS IN SILICA-GEL METHOD FOR SOLID SAMPLE

2132

---