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What is the mode of action of streptomycin/penicillin?
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Answer Posted / roopasunil
β-lactam antibiotics work by inhibiting the formation of
peptidoglycan cross links in the bacterial cell wall. The
beta-lactam moiety of penicillin binds to the enzyme that
links the peptidoglycan molecules in bacteria, and this
weakens the cell wall of the bacterium when it multiplies
(in other words, the antibiotic causes cell cytolysis or
death when the bacterium tries to divide).
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