How the NUCLEOSIDE ANALOGUES ARE USED AS DRUGS?
- 2 Answers
- 4330 Views
- Reddy Labs, I also Faced
- E-Mail Answers
Answer Posted / spandana
Nucleoside analogues 3'azidodeoxythymidine and
2',3'-dideoxycytidine used for the treatment of AIDS.when it
is given to aids patients ,azt and ddcare converted into
triphosphate forms which compete with dttp and dctp as
substrates for dna synthesis.as dna synthesising enzymes of
hiv are sensitive to azt and ddc inhibition these
nucleoside analogues acts as drugs for hiv patients.
| Is This Answer Correct ? | 6 Yes | 0 No |
Post New Answer View All Answers
What are some factors that can lead to protein denaturizing?
Because of dna replication, two dna molecules come to existence. Why is not it correct to assert that two “new” dna molecules are created? What is the name given to the process concerning that fact?
The elution volume of an enzyme on a gel filtration column can be predicted from a) its enzyme activity b) its protein absorbance at 280 nm c) subunit composition and monomer molecular mass(es) d) Choices a) and b) are both correct.
What is the Chemical formula for Epsom salt?
What is the formula of hypo in oxidation state of sulphur?
how I cell disease is caused?
The bond formed between the transition metal ion and ligand is?
What is the importance of the primary structure?
How are free energy changes related to enthalpy changes and entropy changes?
Calculate the molar extinction coefficient of a solution containing 5 *10-4 g litre-1 of a biomolecule, molecular weight 275 g mol-1, and absorbance 0.75 in a 1.2 cm cuvette.
How can energy change in the formation of NACL be determined?
What are pentoses? To what organic group do pentoses belong?
Two children have a neurological disorder. When cells from the two patients were fused to form heterokaryons containing nuclei from both patients and cultured, the cells displayed normal metabolism. Cells from either patient exhibited abnormal metabolism when cultured separately.what does these results indicate?
Differentiate between gram +ve and gram -ve bacteria.
What are the main factors that alter the speed of enzymatic reactions?
