Interested to Buy Any Domain ? << Click Here >> for more details...
What is the importance of the physiologic chloride shift in
erythrocytes?
- 3 Answers
- 24940 Views
- I also Faced
- E-Mail Answers
Answer Posted / biology as student - aspiring
The chloride shift is the diffusion of Chloride anions (Cl-)
from blood plasma into cytoplasm of RBCs and occurs to
maintain the electrochemical neutality in RBCs as
bicarbonate anions (HCO3-)diffuse out of cytoplasm of
erythrocytes (RBCs) into the blood plasma.
The bicarbonate anions are the product of the dissociation
of carbonic acid to bicarbonate and hydrogen ions (H2CO3 ->
HCO3- + H+) with the carbonic acid being formed from
reaction between carbon dioxide and water, this reaction
being catalysed by carbonic anhydrase (H20 + CO2 -> H2CO3).
The protons/hydrogen ions (H+) produced from the
dissociation of carbonic acid go on to react with
haemoglobin causing the tetramer to undergo a 3D
conformational change resulting in the release of an oxygen
molecule from each of the 4 haem prosthetic groups per
haemoglobin tetramer (one per polypeptide subunit). These
diffuse into the blood plasma for respiring tissue. (HbO8 +
H+ -> +HHb + 4O2)
It is this sequence of reactions that account for the Bohr
shift seen on oxygen dissociation curves.
I hope this is right as I have an exam in a few weeks!
| Is This Answer Correct ? | 31 Yes | 7 No |
Post New Answer View All Answers
Which hormones are involved in the urinary sytem of a human body?
Explain the horner's syndrome?
Human anatomy and physiology
You've been given the task of inserting the catheter for a patient scheduled for angioplasty. What anatomical landmarks are you looking for?
What is a structure consisting of 2 or 3 tissues called as?
What does the psychic phase do?
Explain the turner's syndrome?
Explain the anatomy of a human brain?
How many systems are there in a human body? Name them.
Which nerve root is associated with the platella reflexes?
A patient cannot supinate his hand, but has intact feeling-- which portion of the brachial plexus was severed?
After recuperating from a gunshot wound to the buttocks resulting from a hunting accident, your patient exhibits a positive Trendelenburg's sign. Explain.
What does serous membrane do?
Explain the brown-sequard syndrome?
name the structures passing through juglar foramen.
