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wwhat are haemoglobin buffer systems ?explain them?
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Answer Posted / akash
Haemoglobin buffering capacity depends on its oxygenation
and deoxygenation.inside the erythrocytes co2 combines with
H2O to form carbonic acid under the action of carbonic
anhydrase.
at the blood ph 7.4 H2CO3 dessociates into h ion and hco3
ion.
Oxyhaemoglobin on the other side loses O2 to form
deoxyhaemoglobin which remains undessociated.
HBO2 ION->HB ION+O2
HB ION+H2CO3->HHB+HCO3 ION
some of the HCO3 ion diffuses out into plasma to balance
intracellular and plasmabicarbonates. chloride shift takes
place.
HHBO2 produced in lungs by oxygenation of HHB ionises into
H ion and HBO2 ion .
released hydrogens are buffered by hco3 ion inside r.b.c to
form h2co3 which dessociates into h2o and co2 by carbonic
anhydrase.
hco3 return from plasma to r.b.c and escapes in alveoli.
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