Answer Posted / swapna
Angiotensin is an oligopeptide in the blood that causes
vasoconstriction, increased blood pressure, and release of
aldosterone from the adrenal cortex. It is a powerful
dipsogen. It is derived from the precursor molecule
angiotensinogen, a serum globulin produced in the liver. It
plays an important role in the renin-angiotensin system.
Angiotensinogen is an α-2-globulin that is produced
constitutively and released into the circulation mainly by
the liver, although other sites are thought to be involved
also. It is a member of the serpin family, although it is
not known to inhibit other enzymes, unlike most serpins.
Plasma angiotensinogen levels are increased by plasma
corticosteroid, estrogen, thyroid hormone, and angiotensin
II levels.
Angiotensinogen consist of 453 amino acid residues.
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