Question { Cipla, 21800 }

What are the two drugs available for treating AIDS?

Answer

AIDS is acquired immuno deficiency syndrome , up to now
there are no drugs which can claim complete cure of the
disease, drugs are available that can control the virus from
quick replication, usually retroviral drugs are used for the
treatment,the virus is very potent and misuse of the drugs
can lead to resistant strains, hence multi drug therapy is
usually suggested like zidovudine, lamivudine ,stavudine,
acyclovir, guancyclovir etc ,the list goes on.. depending
upon the intensity of the disease

Question { Cipla, 23642 }

why we wre doing linearity siudiec in hplc method validation

Answer

Linearity is done in hplc method validation to show that the
method is linear through out the concentration range i.e.
the hplc method can give results according to the set
concentration , for instance if 1x is the area obtained for
50% solution then for 100% solution it should bee 2X i.e.
and so on. So for every hplc method lineariy is a must

Question { 7678 }

how do u optimise hplc method

Answer

Refer Sniders Practical method development book for hplc