Question { Reddy Labs, 22583 }

DEFINITION OF STABILITY INDICATING METHOD

Answer

The method which studied in the forced degradation
conditions and found that the method is capable to
estimating the degradation of active and impurities as well
and this proves that the method is suitable for stability
studies for short term and long term,regular analysis and
also for shejf life extention of the samples if required.

Question { Ordain Solutions, 8100 }

Dear Sir,
This is Thirunavukkarasu am working in Ordain Health Care
AR&D, Am Having one problem While doing method development
my question Metadoxine and Pyridoxine same chemical nature
and structural activity i tried lot of methods but Analyte
eluted same Retantion time i cant separate both peaks.
solubility, pH both are same only only difference melting
point metadoxine 210 C Pyridoxine 102 C please do the help
needful for me

Answer

Dear SIR,

Kindly play with different pH also...

and also try with RID detector....