Why is buprenorphine less addictive than other opioids (like fentanyl) – is it explainable by its strength of binding to the common receptor, or?
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Answer / Nitin Banshi
Buprenorphine has a partial agonist effect on mu-opioid receptors, which means it binds to the receptor but only produces a partial response. This property helps reduce its addictive potential compared to full opioid agonists like fentanyl.
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