while formulation of Gliclazide floating tablets why we are
using direct cmpression technique why not wet granulation and
what happend with that
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Answer / Santosh Kumar Bhagat
Direct compression is used in the formulation of Gliclazide floating tablets because this method ensures a high content of the active pharmaceutical ingredient (API) in the final product without the need for additional steps such as wet granulation, which could decrease the API content. In wet granulation, excipients are mixed with water or other solvents before adding the API. The resulting slurry is then dried and compressed into tablets. However, this method may require more processing time, increased cost, and potentially lower drug stability compared to direct compression.
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