What do you mean by LOD and water content?
Answers were Sorted based on User's Feedback
Answer / kishor solanke(alkem)
LOD is the loss during drying of sample as per prescribed
conditions which gives loss (presence) of all evaporating
solvents along with water.It is the dry base.
While water content gives the moisture present in the
sample only.It is unhydrous base.
| Is This Answer Correct ? | 23 Yes | 2 No |
Answer / navinpatel
As per USP monograph, Water determination <921>, many
Pharmaceutical substances are either hydrates or contain
water in adsorbed form. As a result, the determination of
the water content is important in demonstrating compliance
with the regulatory standards.
Different methods are used to determine the water content
depending upon the nature of the article or prescribed in
the monographs.
As per USP monograph, Loss on drying <731> is used in those
cases where the loss sustained on heating may be not
entirely water. For substances appearing to contain water
as the only volatile constituent, the procedure given in
the chapter Water determination <921>.
| Is This Answer Correct ? | 6 Yes | 0 No |
Answer / shrikant(mylan)
LOD means remove evaporating solvent including free water.
Water content-remove combined form of water.
| Is This Answer Correct ? | 3 Yes | 0 No |
how impurity is analyzed in a tablet
hi i have done my b pharma and now i am working as a managing director in my own manufacturing unit is there any scope overthere 4 me
how quantitative stability is done
What are the two drugs available for treating AIDS?
What is the difference between temporary change control and deviation?
Discuss the potential side effects and risks associated with Alprazolam usage. How would you manage or mitigate these side effects in a patient?
How can you fix the known and unknown impurity limit for any drug substance?
when will andhara pradesh government announces drug inspector posts and when will be the exam conducted? please inform me..
what are all the needs or pre-requisites to perform project on bracketing and matrixing of stability products?
Discuss the legal and regulatory considerations surrounding the prescription of Alprazolam, including scheduling and documentation requirements.
How can I differentiate between OOS, change control and deviation
1 Answers Dr Reddys, IPCA, Orchid, Orion Laboratories, Zydus Cadila,
calculations of LOD & LOQ