Question { 17880 }

how to prepare 25 ppm acetone. explian with formula

Answer

25mg of acectone->100ml of solvent
further 1ml from 100ml in 10 ml of solvent=25ppm

Question { 10098 }

What is the diffeence between assay and uniformity of content

Answer

assay means the total amount of API present in that tablet.
as per usp 97 to 103, as per IP 95 TO 100.

formula: area of sapmle/area of standard* wt of sample/x *
y/ wt of stanadrd * purity/100 * a.wt/l.c *100.


uniformity of content means in that we have taken 10
samples at a time we check the API in that sample wether it
is uniform or not.

formula: area of sapmle/area of standard* wt of sample/x *
y/ wt of stanadrd * l.c/100.

Question { 13500 }

Which Zone of our country like conducting of Stability
studies(Accelerated & Long term stability studies)as per ICH
guidelines.

Answer

Climatic Zone-iv

Question { 8613 }

In kf constant term 16 what it is explain ?

Answer

In DST there are 2 water molecules form that 2*18= 36


DST m.wt : 236

36/236*100= 15.66

Question { 18560 }

why kbr is used for pellet preparation in ir spectroscopy,
give the reasons? why kbr shows zero dipole moment?

Answer

In IR spectroscopy for the preparation of pellet we use KBR
Because kBR is ir inactive compound,and it catches moisture
in sample, and it does not give any peaks in ir spectra

Question { Laurus, 13101 }

what is the difference between isocratic & elution technique?

Answer

In isocratic we use single mobile phase composition through
out the analysis, where as in gradient two or more mobile
phases are used

Question { Laurus, 10974 }

key components in hplc?

Answer

In HPLC solvent reservior, solvent degassing, pump, column,
injector, detector, recorder,

Question { Laurus, 7608 }

key components in gas chromotagraphy.

Answer

components are Mobile phase, stationary phase, detectors,
injectors,recorder. columns are packed coumns, capiilary
coumns. whrere as detectors are FID,TCD, AIG are used

Question { Cipla, 30414 }

Which column is more polar, C8 or C18?

Answer

when compared to C18, C8 more polar,due to carbon chain increases non polarity increases