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If an enteric coated tablet is taken with milk,will it
disintegrate in stomach or still it will manage to pass
into the intestine and disintegrate in inherent alkaline
environment of intestine?
- 6 Answers
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Answer / aparna
milk is slightly acidic in nature .enteric coating provides
protection to the tablet againt acidic environment,so it
does not disintegrate in the stomach and it will pass into
intestine & disintegrate.
| Is This Answer Correct ? | 23 Yes | 6 No |
Answer / priyaranjan mohapatra
the enteric coated tablet is made for dissolution in
alkaline medium of intestine bcz it doesnot dissolve in
acidic medium............as milk is acid in nature,the drug
can not dissolve in acidic medium of stomach.So it manage
to pass into intestine and dissintigrate in inherent
alkaline medium.......
| Is This Answer Correct ? | 9 Yes | 2 No |
Answer / ivan
enteric-coated dosage forms are designed to be dissolved in basic medium which is why it dissolves in the small intestine. its material for coating protects the drug from premature degradation in the stomach. if it is taken with alkaline substances such as milk, part of it if not all, will be disintegrated thus being inable to exert its effect on the body
| Is This Answer Correct ? | 3 Yes | 1 No |
Answer / naveera nasar
Referring to answer one i guess the whole milk's pH is 6.8
which doesn't lie in acidic range.
| Is This Answer Correct ? | 4 Yes | 4 No |
milk is slightly acidic and the environment of stomach also acidic . These two factors stops the disintegration of enteric coated tablet in the stomach and maintains its stability . But when drug enters into the intestine due to presence of alkaline environment it will undergoes disintegration
| Is This Answer Correct ? | 2 Yes | 2 No |
Answer / pankaj kumar jain (banda)
it will manage to pass
into the intestine and disintegrate in inherent alkaline
environment of intestine.
| Is This Answer Correct ? | 1 Yes | 5 No |
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