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Pace Pharmaceuticals Bio Chemistry Interview Questions
Questions Answers Views Company eMail

What was the primary antibody that was used?

1 3949

Describe how you used that antibody to visualize β-gal protein?

1 5122

Review your data from the entire module. Say we ask you to redo the purification.Is there any step that you could eliminate? Which one? Why can you eliminate it?

2 3419

Why do proteins that recognize specific DNA sequences usually bind in the major groove of DNA?

2 3935

An unusual structure is formed at the 5? end of each cellular mRNA. What is it? After this has formed, does the mRNA have a 5? terminus? Explain.

1 2914

Splicing of pre-mRNA involves an unusual phosphodiester bond. Why is it unusual? What parts of the intron/exon form this bond?

1 3487

Many genes are regulated in both a negative and a positive manner. The genes mediating lactose metabolism in bacteria are a classical example. What are the two small molecule ligands that control expression of these genes? What does each one do?

1 3270

Some proteins profoundly alter the structure of DNA when they bind, bending it far out of its standard B configuration. Where do you think the energy comes from to distort the DNA?

1 3488

Is there a biochemical test for maltose?

2 17093

When starch reacts with iodine, why does it create the characteristic blue-black colour?

5 18587

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Pace Pharmaceuticals Bio Chemistry Interview Questions

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