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Explain the aminoglycosides resistance problem ?

Answer Posted / Vikrant Kumar Nirala

Aminoglycosides resistance in bacteria occurs through various mechanisms, including enzymatic modification of antibiotics (e.g., aminoglycoside modifying enzymes), efflux pump systems that expel antibiotics out of cells, and target site alterations that reduce drug binding to ribosomes. The emergence and spread of multi-drug resistant bacteria is a significant global health concern.

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