ACTH, hypothalamic CRH.

hypothalamus

A secondary lymphoid organ. Has many afferents, one or more
efferents.

With trabeculae. Major histological regions = Follicle,
Medulla, Paracortex.

A Peyer's patch is 'covered' by single layer of cuboidal
enterocytes, interspersed with specialized M cells (no
goblet cells).

9+2 arrangement of microtubules.

1. zona occludens

2. zona adherens

3. Macula adherens

4. gap junction

5. hemidesmosome.

1. skin

2. blood vessels

3. uterus

4. foetal tissue

5. granulation tissue.

1. Nonspecific filtration by macrophages.

2. storage or proliferation of B and T cells

3. Ab production.

1. Mucus-secreting goblet cells of small intestine

2. antibody-secreting plasma cells.

1. M cells take up antigen.

2. stimulated B cells leave Peyer's patch and travel through
lymph and blood to lamina propria of intestine.

3. In lamina propria B cells differentiate into
IgA-secreting plasma cells.

4. IgA receives protective secretory component.

5. IgA is transported across epithelium to gut to deal with
intraluminal Ag.

1. liver hepatocytes

2. steroid hormone-producing cells of adrenal cortex.

1. E-cadherins

2. actin filaments.

1. Distribution center of proteins and lipids from ER to
plasma membrane, lysosomes, secretory vessicles

2. Modifies N-oligosaccharides on asparagine

3. Adds O-oligosaccharides to Ser and Thr residues

4. Proteoglycan assembly from proteoglycan core proteins

5. Sulfation of sugars in proteoglycans and of selected
tyrosine on proteins

6. Addition of mannose-6-phosphate to specific lysosomal
proteins, which targets the protein to the lysosome.

1. Desmoplakin

2. Keratin

desmoplakin and keratin.

1. Cochlear duct

2. utricle.

3. saccule

4. semicircular canals.

1. Cochlea

2. vestibule

3. semicircular canals.