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Categories >> Sciences >> Health-Pharma >> Pharmacy
 
 


 

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Question
how many injection of any concentration should be injected
to determine the LOD/LOD?
Rank Answer Posted By  
 Question Submitted By :: Sunil Kumar
I also faced this Question!!   © ALL Interview .com
Answer
5 injections.
60%,80%,100%,120%,140%.
 
1
Srinivas
 
 
Question
post translation modification 
does not occurs in ... ?
Rank Answer Posted By  
 Question Submitted By :: Guest
This Interview Question Asked @   Hetero , Hetero
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Answer
prokaryotes
 
0
Guest
 
 
Question
in performing of disintigration test in wich condition we use 
the disc&in wich condition we nt use the disk clarify wit 
reasn?
Rank Answer Posted By  
 Question Submitted By :: Hareesh
This Interview Question Asked @   Lupin , Lupin
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Answer
the dosage forms which buoyant in buffer
 
0
Vasu
 
 
 
Answer
we use disk while performing evaluation of transdermal 
products
 
0
Guest
 
 
Answer
As per USP, it is said that disks reduce the disintegration time. hence if we are formulating a faster release drug, then disks are used. 

For example: oral dispersible tablets are evaluated using disks.
 
0
Sreekiran
 
 
Question
what is the exact diff betwen the uniformity of weight & 
uniformity of content?
Rank Answer Posted By  
 Question Submitted By :: Hareesh
This Interview Question Asked @   Lupin
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Answer
Uniformity of content-applies only where the declared quantity of active ingredient in tablets, capsules, oral powders, single-dose oral suspensions or suppositories is 5 mg or less or is 5% or less of the total formulation or, in the case of sugar-coated and enteric-coated tablets.
Uniformity of mass for single-dose preparations does not apply, or for powders for injection or intravenous infusions for which the declared content of active ingredient is 40 mg or less. The test applies to all single-dose suspensions for injection
 
0
Leeladhar
 
 
Answer
uniformity of weight means tablet contain uniformity of weight 
or not. content in uniformity means it contains stated amount 
of drug or not
 
0
Guest
 
 
Question
What is the wavelenght of sodium D-line in Polarimeter?
Rank Answer Posted By  
 Question Submitted By :: Hiren
This Interview Question Asked @   Mylan
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Answer
589nm
 
0
Prakash
 
 
Answer
589.6 nm
 
0
Hiren
 
 
Question
What is sink condition, how far it is maintaining in the
dissolution?
Rank Answer Posted By  
 Question Submitted By :: Gowtami
This Interview Question Asked @   Reddy-Labs
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Answer
Sink condition means maintaining perticulor releasing
concetration at site by constant flowing of fluid
 
0
Raghavendra
 
 
Answer
the volume of medium at least three times that required in order to form a saturated solution of drug substance.
 
0
Jitesh
 
 
Question
how we are selecting the dissolution medium volume like
250ml, 500ml, 900ml, 1000ml?
Rank Answer Posted By  
 Question Submitted By :: Gowtami
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Answer
In stomouch fluid content is 250ml, in interstine it is
500ml, in git fluid content 900ml
 
0
Raghavendra
 
 
Answer
The volume of disso media is basically the sink condition of the drug substance for which dissolution is to be done. Generally 3 to 5 times volume that require in order to form a saturated solution of said drug. Let a drug substance forms a saturated solution using 300 ml then for dissolution of such drug formulation required at least 900 ml or more disso media.
 
0
Manish Kumar Rai
 
 
Question
Why we use basket in place of  bowl in 
dissolution apparatus
Rank Answer Posted By  
 Question Submitted By :: Rushi
This Interview Question Asked @   Torrent-Pharma , Torrent Pharma
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Answer
basket using because to keep the tablet or capsule at
perticulor place. no need to use in case of
suspension,solutions, emulsions etc
 
0
Raghavendra
 
 
Question
why some samples are taking 500mg for water content and some
samples are taken 2g for water content?
Rank Answer Posted By  
 Question Submitted By :: Gowtami.naidu
This Interview Question Asked @   NATCO
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Answer
Test Preparation— Unless otherwise specified in the individual monograph, use an accurately weighed or measured amount of the specimen under test estimated to contain 2-250 mg of water The amount of water depends on the water equivalency factor of the Reagent and on the method of endpoint determination. In most cases, the minimum amount of specimen, in mg, can be estimated using the formula:
FCV / KF
in which F is the water equivalency factor of the Reagent, in mg per mL; C is the used volume, in percent, of the capacity of the buret; V is the buret volume, in mL; and KF is the limit or reasonable expected water content in the sample, in percent. C is between 30% and 100% for manual titration, and between 10% and 100% for the instrumental method endpoint determination.
 
0
Kishor Solanke
 
 
 
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