By using Designer we can create Universes in BO XI R2.

Steps for creating universe by using Quick design wizard:
1)Open Designer with propare credensials, then Designer 
window appeares with Quick design wizard.
2)In Universe parameters enter universe name, and connection
(If required connection not exist create New connection)
3)Create intial Classes and Objects by selecting values 
from database tables.
4) Create intial measure objects if required and click on 
next.
5)the next window shows summary of created 
classes,objects,joins,filters then click on finish

Universe will created successfully.