What is the difference between STANDARDIZATION and CALIBRATION of instrument like KF? why do we standardization of KF everyday? Why the KF factor being only 5.02 etc?
Answers were Sorted based on User's Feedback
Answer / ravindra reddy
calibration means whether instruments working properly or not where as standerdisation means finding the exact strength value of concered solution
Is This Answer Correct ? | 41 Yes | 5 No |
Calibration is related to instrument
Stantardisation is related to the solution
In calibration we check the instrument performance wether working or not by using the standards
1 ml of kf reagent is required to neutralise 5 mg of water so the kf strength is near 5 mg/ml
Actually the kf reagent consist of so2 and I so I present in kf is not stable so we need to check the solution strength daily morning or when ever kf solution is changed
Is This Answer Correct ? | 19 Yes | 2 No |
Answer / naseem khan
Yeah It should be cleared that we do Standardization of Solution and We calibrate to instrument not any Chemical solution.
We find out the unknown concentration of solution by using the known concentration solution, The exact strength of the solution.
Through the calibration we find out whether the perticuler instrument working properly or not to any specific test.
Is This Answer Correct ? | 5 Yes | 0 No |
Answer / geethanath
The KF solution contains Iodine. Which will liberate from the solution. So When Iodine is liberate from the solution the strength of the solution will dicrease. One molicule of iodine will react to one molecule of water. For determining the Iodine strength we have to standardise.
Calibration is a periodic review point to check whether the instrument is working properly or not.
KF factor shold not be equal 5 at every time. The molarity may differ for hygroscopic materils. The diluted KF is having 2.5 as a factor.
Is This Answer Correct ? | 2 Yes | 0 No |
Answer / falguni patel
1ml of KF reagent consumes 5mg of water minimum....so its factor is near 5.
You can see this relation on KF reagent bottle.
Is This Answer Correct ? | 0 Yes | 4 No |
How can we calculate offset value pH measurment
why we are adjusting the ph in buffer solution preparation
How to set analytical specification for combination products?
Which detector is used in uv-vis spectrophotometer?
WAHT IS THE ELUTION ORDER IN GAS CHROMATOGRAPHY?
WHAT IS THE CRITERIA FOR SELECTION OF TIME OF DISSOLUTION AND THE MEDIUM OF DISSOLUTION?
How do we fix the sample concentaryion in hplc method development?
How long we can use hygroscopic reference standard in terms of water absorb.I mean in line with respective monograph's specification or more than that?
what is mean by dissolution hydrodynamics?
what is the difference between heavy metals and sulphated ash
What is the Baseline in HPLC.
When ever we perform system suitability,inject the corresponding standard 6 times why? is thair any reson