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Categories >> Sciences >> Chemistry >> Analytical Chemistry


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whate is difference between calibration and validation
 Question Submitted By :: Analytical-Chemistry
I also faced this Question!!     Answer Posted By  
# 1
Calibration means system performnce checking
Validations mens method of analysis performance checking
Is This Answer Correct ?    46 Yes 8 No
# 2
Calibration is a tool to ensure that the instrument or equipment is working well & Validation is a tool to ensure that the analytical method is working well. 
Is This Answer Correct ?    33 Yes 5 No
# 3
Validation mean documented evidence that a particular
instrument or process produce results meet predetermined
Calibration means particular instrument or device produce
results by comparison of known reference standard.
Is This Answer Correct ?    10 Yes 2 No
Thiruathi Swamy
# 4
Validation in the pharmaceutical and medical device
industry is defined as the documented act of demonstrating
that a procedure, process, and activity will consistently
lead to the expected results.
Making measurements with any analytical method or
instrument requires calibration to ensure the accuracy of
the measurement. There are two common calibration
procedures: using a working curve, and the standard-
addition method. Both of these methods require one or more
standards of known composition to calibrate the
Is This Answer Correct ?    13 Yes 8 No
# 5
will calibratin only for instruments ,. but we can perform
validation not only for instuments for method allso,,..
calibratiom = checking the instrument with standards
validation = validating the existing method or instrument
Is This Answer Correct ?    4 Yes 0 No
Srdhar Kalkode
# 6
Calibration is done by known device (standard)againt the
the unknown device, it means instrument are working
properly or not and can be adjusted within tolerance.

Validation is to ensure the method which is to be used for
its intended purpose or not.
Is This Answer Correct ?    3 Yes 1 No
Chandra Bhushan Tiwari
# 7
Calibration is done to nulify or remove the deviation by comparing with known or reference standard,
while Validation is done to prove that Consistency of expacted results of Process,Method,or Procedure
Is This Answer Correct ?    2 Yes 2 No
Nirav Panchal
# 8
Calibration is done to ensure that the system is ready to
use for any analysis it was just a instrument performance

Validation is to ensure the method which is to be used for
its intended purpose or not.
Is This Answer Correct ?    1 Yes 4 No
K.vineel Kumar

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