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Categories >> Sciences >> Chemistry >> Analytical Chemistry
 
 


 

 
 Organic Chemistry interview questions  Organic Chemistry Interview Questions (222)
 Inorganic Chemistry interview questions  Inorganic Chemistry Interview Questions (96)
 Analytical Chemistry interview questions  Analytical Chemistry Interview Questions (850)
 Physical Chemistry interview questions  Physical Chemistry Interview Questions (57)
 General Chemistry interview questions  General Chemistry Interview Questions (283)
 Chemistry AllOther interview questions  Chemistry AllOther Interview Questions (71)
Question
whate is difference between calibration and validation
 Question Submitted By :: Analytical-Chemistry
I also faced this Question!!     Answer Posted By  
 
Answer
# 1
Calibration means system performnce checking
Validations mens method of analysis performance checking
 
Is This Answer Correct ?    44 Yes 8 No
Raghavaih
 
Answer
# 2
Calibration is a tool to ensure that the instrument or equipment is working well & Validation is a tool to ensure that the analytical method is working well. 
Is This Answer Correct ?    30 Yes 5 No
Siddhesh
 
 
 
Answer
# 3
Validation mean documented evidence that a particular
instrument or process produce results meet predetermined
specification.
Calibration means particular instrument or device produce
results by comparison of known reference standard.
 
Is This Answer Correct ?    9 Yes 2 No
Thiruathi Swamy
 
Answer
# 4
Validation in the pharmaceutical and medical device
industry is defined as the documented act of demonstrating
that a procedure, process, and activity will consistently
lead to the expected results.
Making measurements with any analytical method or
instrument requires calibration to ensure the accuracy of
the measurement. There are two common calibration
procedures: using a working curve, and the standard-
addition method. Both of these methods require one or more
standards of known composition to calibrate the
measurement.
 
Is This Answer Correct ?    13 Yes 8 No
Ragav
 
Answer
# 5
will calibratin only for instruments ,. but we can perform
validation not only for instuments for method allso,,..
calibratiom = checking the instrument with standards
validation = validating the existing method or instrument
 
Is This Answer Correct ?    4 Yes 0 No
Srdhar Kalkode
 
Answer
# 6
Calibration is done by known device (standard)againt the
the unknown device, it means instrument are working
properly or not and can be adjusted within tolerance.


Validation is to ensure the method which is to be used for
its intended purpose or not.
 
Is This Answer Correct ?    3 Yes 1 No
Chandra Bhushan Tiwari
 
Answer
# 7
Calibration is done to nulify or remove the deviation by comparing with known or reference standard,
while Validation is done to prove that Consistency of expacted results of Process,Method,or Procedure
 
Is This Answer Correct ?    2 Yes 2 No
Nirav Panchal
 
Answer
# 8
Calibration is done to ensure that the system is ready to
use for any analysis it was just a instrument performance
check.

Validation is to ensure the method which is to be used for
its intended purpose or not.
 
Is This Answer Correct ?    1 Yes 4 No
K.vineel Kumar
 

 
 
 
Other Analytical Chemistry Interview Questions
 
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how can standardized of HCl of 0.1 N   6
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what is the relation of normality & molarity ? give me formula?   3
WHAT ARE THE PRIMARY STANDARDS?   4
IS THERE ANYWHERE MENTION THAT THE RE PROCESS BATCH REQUIRE TO KEPT STABILITY STYDY Nakoda-Chemicals 1
Generally for Normal Phase HPLC,stationary phase is Polar.In place of polar if we take non-polar means what happened & why?   7
why in hplc peaks are in positive side(it means upside) not in negative side?   2
how ir specrometer is calibrated ?   1
why we are using polystyrene film for calibration of I.R spectroscopy? Reddy-Labs 9
Why caffeine as a reference standard used for calibration of HPLC? Orchid 11
 
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