minimum weight you can measured is called least count of
the analytical balance.By weighing subsequent low weights ,
at which level the weight is not deviating from the
standard weight by 0.01% ,that should be considered as
least count.For denver analytical balances it is 20 mg, for
micro balance is 0.01mgand for pan balance it is 2 gram
The least count of the balance has been given in the balance
itself.Otherwise place the weight in the balnce and check
the result in the balance.If the result shows for 1kg i.e
1.001 then the lease count of the balance is 0.001kg.
stability study is going on up to 3years for famotidine-USP but the pharmacopeia is revised and tlc test is replaced with hplc test. At the 4th year frequency the product is failed in hplc test .how can i assain the expiry or retest date and can i stop or continue the programme?