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Categories >> Sciences >> Health Pharma >> Pharmacy


 Pharmacy interview questions  Pharmacy Interview Questions (220)
 Lab Technicians interview questions  Lab Technicians Interview Questions (73)
 Health Pharma AllOther interview questions  Health Pharma AllOther Interview Questions (82)
what is sink condition in Dissolution?
 Question Submitted By :: Pharmacy
I also faced this Question!!     Answer Posted By  
# 1
In general the dissolution medium volume should be 3-10
times the saturation solubulity of the drug. Sink
conditions means thd drug which goes in to the solution is
not effected by the drug which not dissolved.
Is This Answer Correct ?    140 Yes 33 No
# 2
In sink condition, the volume of Medium is more than 5-10 folds of its saturation point & in anyway it Drug will not reach to its saturation point. 
Is This Answer Correct ?    30 Yes 11 No
Indra Kumar Gupta
# 3
which should be able to dissolve the expected amount of drug released from a product. This ability of the medium to dissolve the expected amount of drug is known as a “sink condition" 
Is This Answer Correct ?    6 Yes 2 No
K.gopal Rao
# 4
One of the requirements to conduct an appropriate drug
dissolution test is to use a sufficient volume of
dissolution medium, which should be able to dissolve the
expected amount of drug released from a product. This
ability of the medium to dissolve the expected amount of
drug is known as a “sink condition”.It is important to note
that a dissolution test should not be conducted in a volume
of the medium which would not dissolve the expected amount
of the drug completely and freely.
Is This Answer Correct ?    11 Yes 9 No
Ganesh Parsewar
# 5
The concentration of drug at absorption site i.e.,GIT is more than in plasma level.....
It follows first order reaction(non linear graph)
Is This Answer Correct ?    8 Yes 10 No
N Bharth Kumar
# 6
accordng to ficks first low c git is zero compare to c plasma .if have zero condition disslution is high 
Is This Answer Correct ?    3 Yes 11 No
# 7
it is the condition at which the concentration of drug in
git is maintain greater then that of in plasma.
Is This Answer Correct ?    2 Yes 11 No
Pankaj Kumar
# 8
how much drug absorb its eliminated in same amount 
Is This Answer Correct ?    3 Yes 26 No
# 9
it is a condition at which the concentration of drug is
maintain in blood after administration of drug due to
continuous flow of blood
Is This Answer Correct ?    35 Yes 62 No

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what is relative response factor in related substance   1
in performing of disintigration test in wich condition we use the disc&in wich condition we nt use the disk clarify wit reasn? Lupin 3
basic of hplc,columns used   1
what is the major definition and difference between uniformity of content and content uniformity as official test for all tablets? Wockhardt 3
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