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Categories >> Sciences >> Chemistry >> Analytical Chemistry


 Organic Chemistry interview questions  Organic Chemistry Interview Questions (227)
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 Analytical Chemistry interview questions  Analytical Chemistry Interview Questions (859)
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What is primary & Secondary Standard ? Give Example
 Question Submitted By :: Analytical-Chemistry
I also faced this Question!!     Answer Posted By  
# 1
Primary standard :
Primary standards are the materials having high purity
values under specified conditions which can be used to
standardise the volumetric solutions.This primary stadards
also used to prepare the solutions which are necessay for
the calibration of analytical instruments.

Secondary standards:
Generally volumetric solutions are
known as secondary standards
Is This Answer Correct ?    107 Yes 30 No
# 2
Primary standard are the compounds having reagent(analyte)
of high purity and can directly used for perpration of
standard solutions.
Example:- Nacl is primary standard for AgNO3
NaOH is primary standard for HCl

Secondary Standard solutions are analysed against primary
standard solutions. Basically these are perpared in
laboratory for specific analysis.
Is This Answer Correct ?    12 Yes 5 No
Kamal Kishore Kashyap
# 3
For example in pharmaceutical chemistry primary standard will be pharmacopoeia's standard - USP or CRS, but they are very expensive. So you can fully characterize your "in house" material as your primary standard and use it for analysis. All next batch of standard, characterized vs. primary will be secondary standard. A part of primary standard should be stored for secondary standards characterizations. 
Is This Answer Correct ?    23 Yes 23 No
# 4
primary std thats stdrd solution can be prepare but secondry thats stdnrd solution can not be prepared

eg. acetic acid is primary std but sulfuric acid is secondry
Is This Answer Correct ?    3 Yes 6 No
Nisha (college Student)
# 5
Primary standard :
the Primary standards are the NIST ,ISO ASC Standard
tracible materials
.This primary stadards
the solutions which are use for
the calibration of analytical instruments.
also used to standardization of std( Normal & Molar solution

Secondary standards:
are use to routine analysis known as
secondary standards for but Secondary standards are liquid
calibration of analytical instruments.
also used to standardization of std( Normal & Molar solution
Is This Answer Correct ?    36 Yes 53 No
Kishanpal Singh Fare Labs Gurg

Other Analytical Chemistry Interview Questions
  Question Asked @ Answers
In Force degradation Study Compound is not degrade in any condition , also in higher stress what can i do ? Alembic 4
differnc btw c18 and c-8 column Cipla 2
WHY POTASSIUM HYDROGEN PTHALATE IS USED FOR PERCHLORIC ACID? What is difference btw UV detector & RID detector? what is dissolution? What is unit of KF? what is the significant of pH in HPlc?   1
What is the difference between Primay and Secondry Standard ? Neuland 6
what is difference between IR & FTIR ? how we calibarte both ? I want to know the procedure. Cadila 6
what is the difference between the Purity and Potency of drug substance Divis-Laboratories 1
why RID detector is used for selective materials like Mannitol, Hydroxyethyl Starch and Sorbitol?   4
What is principle of Polarimeter? Intas 21
why buffer is added in solvent system in HPLC ?? Lupin 8
When performing Moisture content how to you say only Methanol react with water not product Explain? Orchid 2
in hplc calibration we are using 0.05% acetone why we are using that one and what happen when its conc increases or decreases Cadila 1
How can the GC or HPLC method is selected to determine the impurity profile in drug product? Ajanta 1
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